Magnesium

Magnesium is a Mineral supplement available in 1 form.

Not all forms of Magnesium are equal. The form you choose determines how much Magnesium actually reaches your tissues, and the difference between the best and worst forms can be substantial. Magnesium bisglycinate chelate (Albion TRAACS) delivers up to 4-7x greater absorption than magnesium oxide, the most common supplement form. The chelated glycine carrier uses amino acid transport channels rather than competing for mineral absorption pathways, resulting in significantly less GI distress — a common reason patients discontinue magnesium supplementation.

Magnesium (as Albion® Magnesium Bisglycinate Chelate Buffered) Preferred (T1 Preferred) has a bioavailability rating of good (S2). Typical dose range: not yet documented in our database.

Magnesium bisglycinate chelate is one of the most bioavailable forms of magnesium, with research indicating superior absorption compared to magnesium oxide (up to 4-7x difference in bioavailability). The chelated glycine carrier allows absorption through amino acid transport channels, resulting in less GI distress. Albion TRAACS chelate is the gold-standard form used in clinical research, with published studies supporting its use for sleep quality, muscle recovery, and stress response support.

Magnesium bisglycinate chelate showed significantly higher bioavailability compared to magnesium oxide in human crossover study PMID: 14596323

Magnesium citrate demonstrated superior absorption vs oxide in balanced crossover design PMID: 7815675

Systematic review confirming organic magnesium salts superior to inorganic forms for bioavailability PMID: 39770988

Magnesium (as Albion® Magnesium Bisglycinate Chelate Buffered) is classified as T1 Preferred in the FormulaForge formulary — our top recommendation for Magnesium. It carries a bioavailability rating of good (S2), meaning more of the active compound reaches your tissues per dose unit compared to lower-tier forms.

When choosing a Magnesium supplement, look for the S1 (best absorption) bioavailability tier on the label or formulary listing. T1 Preferred forms have the strongest research-backed evidence for efficient absorption.

Other forms may be appropriate depending on individual goals, cost considerations, and your healthcare provider’s guidance. The best form for you depends on your specific health needs.

For Magnesium (as Albion® Magnesium Bisglycinate Chelate Buffered), the typical dosing range is not yet documented in our database. Individual dose requirements vary based on health goals, body weight, and existing nutrient intake.

Side Effects: Specific side effect data for these forms is not yet documented in our database. In general, consult your healthcare provider regarding tolerability at higher doses.

These statements are based on structure/function research and have not been evaluated by the FDA. This information is not intended to diagnose, treat, cure, or prevent any disease. Always consult a qualified healthcare provider before starting or changing a supplement regimen.

The following studies and findings inform our formulary classifications for Magnesium:

Magnesium bisglycinate chelate showed significantly higher bioavailability compared to magnesium oxide in human crossover study PMID: 14596323

Magnesium citrate demonstrated superior absorption vs oxide in balanced crossover design PMID: 7815675

Systematic review confirming organic magnesium salts superior to inorganic forms for bioavailability PMID: 39770988

Magnesium L-threonate uniquely elevates brain magnesium levels via blood-brain barrier penetration PMID: 29630135

Fractional absorption of magnesium oxide approximately 4% in human subjects PMID: 11794633

Magnesium glycinate and citrate show equivalent bioavailability in healthy subjects PMID: 20152124

Chelated magnesium forms show improved tolerability and reduced laxative effect PMID: 36558392

Elemental magnesium content varies significantly across salt forms affecting dosing equivalence PMID: 8587088