Best Supplements for Anxiety Support

Several well-studied ingredients may support a calm, balanced stress response as part of a healthy lifestyle. Research suggests that certain minerals, adaptogenic botanicals, and essential fatty acids play roles in nervous system function and healthy mood regulation. FormulaForge ranks every ingredient by bioavailability so you select the most effective forms.

Updated 2026 · Reviewed by Dr. Brennan Commerford, D.C.

Research-Backed Ingredients

Related ingredients that support this goal

Frequently Asked Questions

What supplements may support a healthy anxiety response?

Ingredients such as Magnesium Glycinate, Ashwagandha (KSM-66 or Sensoril), and Omega-3 fatty acids are commonly included in wellness routines aimed at supporting a healthy stress response. These supplements are not intended to diagnose, treat, cure, or prevent any disease, including anxiety disorders. Consult a qualified healthcare provider for clinical concerns.

What is the best form of magnesium for calm support?

Magnesium Glycinate (Bisglycinate) is our top-ranked form for supporting healthy relaxation. It demonstrates superior bioavailability compared to oxide or carbonate forms, and research suggests magnesium plays a role in healthy nervous system function.

How does ashwagandha support a healthy stress response?

Ashwagandha is an adaptogenic botanical traditionally used to support the body's response to everyday stressors. Concentrated extracts such as KSM-66 and Sensoril are the most studied forms. These are structure/function claims — ashwagandha is not a treatment for anxiety disorders.