The Women's Health Formula — Forms That Work for the Female Body
Eight ingredients for normal hormonal balance, cycle comfort, iron status, and stress resilience — each in a studied form, at doses drawn from published research.
Customize this formulaThe Formula
8 ingredients · 14 capsules/day · Each dose is study-attributed — see citations in line.
Myo-Inositol
Myo-inositol is the most abundant inositol isomer in human tissue, where it serves as a building block for the phosphoinositide signaling molecules involved in insulin signal transduction; 2000 mg/day sits at the lower end of the 2–4 g/day amounts most commonly used in clinical research.
Ashwagandha (Withania somnifera) Root Extract
A 2012 randomized double-blind trial (PMID 23439798, n=64) found 300 mg twice daily (600 mg/day) of a standardized ashwagandha root extract significantly reduced cortisol and stress scores over 8 weeks in adults with chronic stress. (PMID 23439798)
Vitex (Chaste Tree Berry Extract)
A 2012 randomized trial (PMID 23022391, n=162) found 20 mg/day Ze440 standardized Vitex extract significantly improved premenstrual syndrome symptom scores vs. placebo over three cycles; the low dose reflects the highly concentrated standardized extract ratio rather than crude herb powder. (PMID 23022391)
Diindolylmethane (DIM)
DIM is formed from indole-3-carbinol, a compound in cruciferous vegetables. Emerging research on DIM and estrogen metabolism is mixed: a 2017 randomized trial (PMID 28560655; 130 women taking tamoxifen for breast cancer prevention or after early-stage breast cancer randomized, 98 completed; 300 mg/day) reported a higher urinary 2/16α-hydroxyestrone ratio, while a 30-day randomized trial in premenopausal women with a low baseline ratio (PMID 36111381; n=60; 75 mg/day) found no significant increase in a closely related urinary ratio (2-hydroxyestrogens to 16α-hydroxyestrone), and a 12-month single-arm study in BRCA mutation carriers at this formula's 100 mg/day dose (PMID 32458980; 23 women completed) found no significant change in urinary estrogen metabolites. The 2017 trial also found that DIM lowered blood levels of active tamoxifen metabolites, including endoxifen, so anyone taking tamoxifen should not start or continue DIM without talking to their oncologist. We believe this needs further study and verification. Consult your physician before starting DIM.
Ferrochel® — Iron (as Ferrochel® Ferrous Bisglycinate Chelate)
Ferrochel® ferrous bisglycinate chelate is an iron form developed for tolerability; 18 mg elemental is the RDA-matched maintenance dose for premenopausal women. Bisglycinate chelate forms are broadly studied for improved GI tolerability compared to ferrous sulfate.
Quatrefolic® — Folate (as Quatrefolic® L-5-methyltetrahydrofolate)
A randomized crossover trial (PMID 16825690) found [6S]-5-MTHF increased red blood cell folate more effectively than folic acid at equivalent doses; Quatrefolic® provides L-5-MTHF — the bioactive folate — bypassing the enzymatic conversion step that a common MTHFR variant impairs. (PMID 16825690)
Albion® Magnesium Bisglycinate — Magnesium (as Albion® Bisglycinate Chelate Buffered)
Bisglycinate chelate is selected for improved absorption and tolerability compared to magnesium oxide (approximately 4% for oxide, PMID 11794633); adequate magnesium is associated with improved menstrual comfort and mood in multiple randomized trials. (PMID 11794633)
Vitamin D3
A large randomized trial (PMID 30415629, n=25,871) used 2000 IU/day vitamin D3 as the studied maintenance dose; 2000 IU/day is a widely studied dose for women with baseline insufficiency. (PMID 30415629)
Why One Formula Beats the Stack
Sourcing these ingredients separately requires 7 bottles and 22 pills per day — vs. 14 capsules in this formula.
22
pills/day (separate bottles)
14
capsules/day (this formula)
Form Quality Gaps
The commodity versions most single-ingredient bottles use — and why they fall short.
| FormulaForge Form | Commodity Default | What the Research Shows |
|---|---|---|
| Quatrefolic® L-5-methyltetrahydrofolate | Folic acid | A randomized crossover trial (PMID 16825690) found L-5-MTHF increased red blood cell folate more effectively than folic acid at equivalent doses; Quatrefolic® provides the pre-converted active folate for individuals with impaired enzymatic conversion. |
| Ferrochel® Ferrous Bisglycinate Chelate iron | Ferrous sulfate | A 2023 noninferiority trial (PMID 37271416) found 18 mg ferrous bisglycinate was associated with lower ferritin increases than 60 mg ferrous sulfate (84 vs 99 μg/L) in Cambodian women — using roughly one-third the elemental iron — though it did not meet the prespecified noninferiority margin. A 2023 systematic review and meta-analysis (PMID 36728680) found ferrous bisglycinate was associated with fewer gastrointestinal adverse events than other iron supplements (incidence rate ratio 0.36, p<0.01) in pregnant women.See the evidence → |
| Albion® Magnesium Bisglycinate | Magnesium oxide | Magnesium oxide has approximately 4% intestinal fractional absorption in controlled studies (PMID 11794633), making it largely ineffective for addressing common magnesium insufficiency despite its high elemental content on a label. |
Pricing context
Seven separate women's health supplements from well-known brands typically cost $90–$130/month. This formula's live quote usually comes in below that — with Quatrefolic®, Ferrochel®, and Albion® chelates that most under-$20 single bottles don't include.
Exact pricing is quoted live in the builder based on your personalized formula. Example figures are illustrative only and reflect in-one example market research — not a guaranteed price or saving.
This is a starter — you customize it
Every ingredient and dose is adjustable. Add ingredients, swap forms, change doses, or remove anything that doesn't fit your situation. The builder gives you a live price quote as you go.
Frequently Asked Questions
Is this formula appropriate for pregnancy?
No formula on this platform is designed for or labeled as safe for pregnancy without physician oversight. Myo-Inositol and Vitex have specific research contexts that may not apply during pregnancy. Always consult your OB-GYN or midwife before starting any supplement during pregnancy or when trying to conceive.
Why is the Vitex dose only 20 mg?
Vitex Ze440 is a highly concentrated standardized extract, not crude herb powder. The clinically studied dose in the randomized trial (PMID 23022391) is 20 mg of this specific extract. The low label dose is a feature of the high standardization.
Is this formula intended for a medical condition?
No. This is a general women's wellness starting point built around normal hormonal, metabolic, and iron-status function — it is not intended to diagnose, treat, cure, or prevent any disease. If you have a diagnosed condition, talk with your physician before starting, and remove or adjust any ingredient in the builder to match your situation.
Why does this include DIM?
DIM (Diindolylmethane) is a concentrated plant compound, not a hormone. Human research on DIM and estrogen metabolism is emerging and mixed: a randomized trial in women taking tamoxifen for breast cancer prevention or after early-stage breast cancer reported a higher urinary 2/16α-hydroxyestrone ratio at 300 mg/day (PMID 28560655), while a randomized trial in premenopausal women with a low baseline ratio at 75 mg/day found no significant increase in a closely related urinary ratio (PMID 36111381), and a single-arm study in BRCA mutation carriers at this formula's 100 mg/day dose found no significant change in urinary estrogen metabolites (PMID 32458980). The tamoxifen trial also found that DIM lowered blood levels of active tamoxifen metabolites, including endoxifen. We believe this needs further study and verification. You can remove or adjust DIM in the builder, and consult your physician before starting it. If you take tamoxifen, do not start or continue DIM without talking to your oncologist; if you take any other hormone-related medication, talk with your physician first.