ByDr. Brennan Commerford, Chiropractic Physician·Last reviewed: April 2026

Best Supplements for Inflammation Support

The body's inflammatory response is a normal physiological process, and certain nutrients play important roles in supporting healthy inflammatory balance. Research suggests that Omega-3 fatty acids, Vitamin D, and Magnesium each contribute to the body's healthy inflammatory signaling pathways. Our formulary ranks every ingredient by the bioavailability of its available forms.

Updated 2026 · Reviewed by Dr. Brennan Commerford, D.C.

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Research-Backed Ingredients

Frequently Asked Questions

What supplements may support a healthy inflammatory response?
Omega-3 fatty acids (as EPA and DHA), Vitamin D3, and Magnesium Glycinate are commonly included in inflammation-support wellness routines. These supplements are not intended to diagnose, treat, cure, or prevent any inflammatory disease. Consult your healthcare provider for clinical guidance.
What is the best form of omega-3 for inflammation support?
Triglyceride-form Omega-3 (re-esterified TG fish oil) and krill oil (phospholipid-bound Omega-3) demonstrate superior bioavailability over ethyl ester forms. EPA in particular is associated with supporting a healthy inflammatory balance in research literature.
Does vitamin D support healthy inflammation balance?
Vitamin D receptors are found on numerous immune and inflammatory cells, and research suggests that adequate Vitamin D levels support healthy inflammatory signaling. Vitamin D3 (Cholecalciferol) is our top-ranked form for superior bioavailability over Vitamin D2. These are structure/function claims only.

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*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

FormulaForge formulates and sells supplements containing the ingredients discussed on this page. Our formulary recommendations are based on peer-reviewed bioavailability research. All cited studies are independently verifiable.