Vitamin1 form

Vitamin K2

Preferred Form

MK-7

Form Score

100/100Top Tier

Evidence Level

Moderate Evidence

The Vitamin K2 form we carry

See how we score it — absorption, bioavailability & formulary tier

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Quick Answer

Which form of Vitamin K2 do we use?

MK-7 is the form of Vitamin K2 we carry — the only form in our formulary, recommended for its exceptional bioavailability.

All Forms of Vitamin K2

Form	Tier	Form Score	Dose Range	Unit
MK-7	Preferred	100/100Top Tier	—	—

Absorption by Form

Top Tier

MK-7

100/100

What is Vitamin K2?

Vitamin K2 is a Vitamin supplement available in 1 form.

FormulaForge carries a single form of Vitamin K2, so there is no form to choose here. Forms on the market do differ in how well they absorb, which is why it is worth checking the form named on any product label.

The Form of Vitamin K2 We Carry

Vitamin K2 (as MK-7) Preferred (Preferred Form) has a bioavailability rating of high absorption.

How to Choose the Right Form

Vitamin K2 (as MK-7) is classified as Preferred Form by FormulaForge — our top recommendation for Vitamin K2. It carries a bioavailability rating of high absorption, meaning more of the active compound reaches your tissues per dose unit compared to lower-rated forms.

When choosing a Vitamin K2 supplement, read the label for the specific form name — that is what determines how much you actually absorb. Preferred Forms have the strongest research-backed evidence for efficient absorption.

Other forms may be appropriate depending on individual goals, cost considerations, and your healthcare provider’s guidance. The best form for you depends on your specific health needs.

Dosing & Safety

Individual dose requirements vary based on health goals, body weight, and existing nutrient intake. Your healthcare provider can help you determine an appropriate amount of Vitamin K2 for you.

Side Effects: Consult your healthcare provider regarding tolerability, particularly at higher doses.

These statements are based on structure/function research and have not been evaluated by the Food and Drug Administration. This information is not intended to diagnose, treat, cure, or prevent any disease. Always consult a qualified healthcare provider before starting or changing a supplement regimen.

The Science

The following studies and findings inform FormulaForge classifications for Vitamin K2:

Crossover RCT (n=5 healthy women): single dose MK-4 (420μg) was undetectable in serum at all time points; MK-7 (420μg) reached peak serum concentration at 6 hours and was detectable up to 48 hours post-intake. Consecutive daily MK-7 produced significant cumulative serum accumulation; MK-4 showed none. PMID: 23140417

Healthy volunteers: natto-derived MK-7 accumulated 7-8 fold higher serum levels than synthetic vitamin K1 (phylloquinone) during prolonged supplementation. MK-7 induced more complete carboxylation of osteocalcin (extrahepatic tissue marker) vs K1. Both absorbed with peak at 4 hours; MK-7 sustained versus K1 rapid decline. PMID: 17158229

Review: Postprandial serum MK-7 concentrations reported 10-fold higher than K1 (phylloquinone). K1 primarily retained in liver for coagulation; MK-7 redistributes to extrahepatic tissues (bone, vasculature) due to longer circulating half-life. Long-chain menaquinones detectable up to 96 hours vs 8-24 hours for K1. PMID: 30791399

Dosing Guidance

Individual dose requirements for Vitamin K2 vary based on health goals, body weight, and existing dietary intake. A qualified healthcare provider can help you determine an appropriate amount for you.

Frequently Asked Questions

Which form of Vitamin K2 is in our formulary?

Our formulary carries a single form of Vitamin K2: MK-7. It has exceptional bioavailability, meaning your body absorbs and uses it efficiently.

How much Vitamin K2 should I take?

Dosing for Vitamin K2 varies based on the specific form, your health goals, and individual factors. Consult a qualified healthcare provider for personalized guidance.

What does Vitamin K2 support?

Vitamin K2 is commonly used to support Vitamin. Research suggests it plays a role in several physiological pathways. As with all supplements, these statements have not been evaluated by the Food and Drug Administration and Vitamin K2 is not intended to diagnose, treat, cure, or prevent any disease.

Is Vitamin K2 safe?

Vitamin K2 is generally well-tolerated when taken at research-supported doses. As with any supplement, individual responses vary. Consult a qualified healthcare provider before use, especially if you are pregnant, nursing, have a medical condition, or take medications. These statements have not been evaluated by the Food and Drug Administration.

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References

Crossover RCT (n=5 healthy women): single dose MK-4 (420μg) was undetectable in serum at all time points; MK-7 (420μg) reached peak serum concentration at 6 hours and was detectable up to 48 hours post-intake. Consecutive daily MK-7 produced significant cumulative serum accumulation; MK-4 showed none. PubMed
Healthy volunteers: natto-derived MK-7 accumulated 7-8 fold higher serum levels than synthetic vitamin K1 (phylloquinone) during prolonged supplementation. MK-7 induced more complete carboxylation of osteocalcin (extrahepatic tissue marker) vs K1. Both absorbed with peak at 4 hours; MK-7 sustained versus K1 rapid decline. PubMed
Review: Postprandial serum MK-7 concentrations reported 10-fold higher than K1 (phylloquinone). K1 primarily retained in liver for coagulation; MK-7 redistributes to extrahepatic tissues (bone, vasculature) due to longer circulating half-life. Long-chain menaquinones detectable up to 96 hours vs 8-24 hours for K1. PubMed

FormulaForge formulates and sells supplements containing the ingredients discussed on this page. Our formulary recommendations are based on peer-reviewed bioavailability research. All cited studies are independently verifiable.