Indole-3-Carbinol (I3C)

Indole-3-Carbinol (I3C) is a Specialty supplement available in 1 form.

FormulaForge carries a single form of Indole-3-Carbinol (I3C), so there is no form to choose here. Forms on the market do differ in how well they absorb, which is why it is worth checking the form named on any product label.

Indole-3-Carbinol (I3C) (Secondary Form) has a bioavailability rating of good absorption.

Indole-3-Carbinol (I3C) is a glucosinolate breakdown product from cruciferous vegetables that supports Phase I estrogen metabolism. In the stomach, I3C converts to DIM and other metabolites. Research supports I3C for estrogen balance, with studies demonstrating shifts toward favorable 2-hydroxy estrogen metabolites. It complements DIM supplementation by providing upstream pathway support.

Multiple forms of Indole-3-Carbinol (I3C) are available. Start by comparing form ratings — Preferred Forms reflect the strongest bioavailability evidence, and higher-absorption forms deliver more active compound per dose unit.

The appropriate form depends on your individual goals and your healthcare provider’s recommendations. Consult a qualified professional before selecting a supplement form.

Individual dose requirements vary based on health goals, body weight, and existing nutrient intake. Your healthcare provider can help you determine an appropriate amount of Indole-3-Carbinol (I3C) for you.

Side Effects: Consult your healthcare provider regarding tolerability, particularly at higher doses.

These statements are based on structure/function research and have not been evaluated by the Food and Drug Administration. This information is not intended to diagnose, treat, cure, or prevent any disease. Always consult a qualified healthcare provider before starting or changing a supplement regimen.