Indole-3-Carbinol (I3C)

Indole-3-Carbinol (I3C) is a Specialty supplement available in 1 form.

Not all forms of Indole-3-Carbinol (I3C) are equal. The form you choose determines how much Indole-3-Carbinol (I3C) actually reaches your tissues, and the difference between the best and worst forms can be substantial. Indole-3-carbinol (I3C) is the natural cruciferous vegetable compound that converts to DIM and other acid condensation products in the stomach, providing a broader spectrum of indole metabolites than DIM alone. Research supports I3C for promoting healthy estrogen metabolism, Nrf2 pathway activation, and cellular health.

Indole-3-Carbinol (I3C) (Secondary Form) has a bioavailability rating of good absorption.

Indole-3-Carbinol (I3C) is a glucosinolate breakdown product from cruciferous vegetables that supports Phase I estrogen metabolism. In the stomach, I3C converts to DIM and other metabolites. Research supports I3C for estrogen balance, with studies demonstrating shifts toward favorable 2-hydroxy estrogen metabolites. It complements DIM supplementation by providing upstream pathway support.

Multiple forms of Indole-3-Carbinol (I3C) are available. Start by comparing form ratings — Preferred Forms reflect the strongest bioavailability evidence, and higher-absorption forms deliver more active compound per dose unit.

The appropriate form depends on your individual goals and your healthcare provider’s recommendations. Consult a qualified professional before selecting a supplement form.

Individual dose requirements vary based on health goals, body weight, and existing nutrient intake. Your healthcare provider can help you determine an appropriate amount of Indole-3-Carbinol (I3C) for you.

Side Effects: Consult your healthcare provider regarding tolerability, particularly at higher doses.

These statements are based on structure/function research and have not been evaluated by the Food and Drug Administration. This information is not intended to diagnose, treat, cure, or prevent any disease. Always consult a qualified healthcare provider before starting or changing a supplement regimen.