Best Supplements for Skin, Hair & Nails

Healthy skin, hair, and nails depend on adequate structural proteins, hydration-supporting molecules, and antioxidant protection from oxidative stress. Research suggests that collagen peptides, hyaluronic acid, and astaxanthin each support distinct aspects of skin structure, moisture, and resilience. FormulaForge ranks every ingredient by the bioavailability of its available forms so you can choose the most effective options.

Updated 2026 · Reviewed by Dr. Brennan Commerford, D.C.

Research-Backed Ingredients

Frequently Asked Questions

What supplements may support healthy skin, hair, and nails?

Hydrolyzed collagen peptides, oral hyaluronic acid, and astaxanthin are among the most studied ingredients for supporting healthy skin elasticity, hydration, and resilience. These supplements are not intended to diagnose, treat, cure, or prevent any skin disease or condition. Consult a qualified healthcare provider for persistent skin concerns.

Do collagen peptides support skin elasticity?

Hydrolyzed collagen peptides have been studied for supporting skin elasticity and hydration. A randomized, placebo-controlled trial in women (Bolke et al. 2018; PMID 30122200) reported that daily oral collagen peptides combined with cofactors were associated with improved skin elasticity versus placebo. These are structure/function observations — collagen is not a treatment for any skin condition.

Can oral hyaluronic acid support skin moisture?

Hyaluronic acid is a molecule naturally present in skin that helps retain moisture. A randomized, double-blind, placebo-controlled trial (Goncalves et al. 2021; PMID 34933842) reported that oral full-spectrum hyaluronan was associated with improvements in skin profilometry and signs of aging versus placebo. These are structure/function claims only.

What does astaxanthin do for skin?

Astaxanthin is a carotenoid antioxidant studied for supporting skin against oxidative stress. A comparative placebo-controlled study (Yoon et al. 2014; PMID 24955642) reported that dietary astaxanthin was associated with improved facial elasticity. Research suggests astaxanthin may support healthy skin resilience. These are structure/function claims.