Urolithin A

Urolithin A is a Specialty supplement available in 1 form.

Not all forms of Urolithin A are equal. The form you choose determines how much Urolithin A actually reaches your tissues, and the difference between the best and worst forms can be substantial. Urolithin A is a gut microbiome metabolite of ellagitannins (from pomegranate and berries) that directly activates mitophagy—the selective removal of damaged mitochondria. As a pure, bioavailable form, research supports urolithin A for promoting healthy mitochondrial quality control and muscle function, particularly for individuals whose gut microbiome cannot efficiently produce it from dietary precursors.

Urolithin A Preferred (T1 Preferred) has a bioavailability rating of good (S2). Typical dose range: not yet documented in our database.

Urolithin A is a postbiotic metabolite that activates mitophagy — the selective cleanup of damaged mitochondria. Only ~40% of people produce adequate urolithin A from dietary pomegranate, making direct supplementation valuable. Clinical trials demonstrate improved mitochondrial function, muscle endurance, and cellular aging biomarkers. It is the first clinically validated mitophagy activator.

Urolithin A is classified as T1 Preferred in the FormulaForge formulary — our top recommendation for Urolithin A. It carries a bioavailability rating of good (S2), meaning more of the active compound reaches your tissues per dose unit compared to lower-tier forms.

When choosing a Urolithin A supplement, look for the S1 (best absorption) bioavailability tier on the label or formulary listing. T1 Preferred forms have the strongest research-backed evidence for efficient absorption.

Other forms may be appropriate depending on individual goals, cost considerations, and your healthcare provider’s guidance. The best form for you depends on your specific health needs.

For Urolithin A, the typical dosing range is not yet documented in our database. Individual dose requirements vary based on health goals, body weight, and existing nutrient intake.

Side Effects: Specific side effect data for these forms is not yet documented in our database. In general, consult your healthcare provider regarding tolerability at higher doses.

These statements are based on structure/function research and have not been evaluated by the FDA. This information is not intended to diagnose, treat, cure, or prevent any disease. Always consult a qualified healthcare provider before starting or changing a supplement regimen.