Shiitake

Shiitake is a Specialty supplement available in 1 form.

FormulaForge carries a single form of Shiitake, so there is no form to choose here. Forms on the market do differ in how well they absorb, which is why it is worth checking the form named on any product label.

Shiitake Preferred (Preferred Form) has a bioavailability rating of good absorption.

Shiitake (Lentinula edodes) extract provides lentinan — a beta-glucan with extensive clinical research for immune modulation. Research demonstrates enhanced NK cell activity, macrophage activation, and cytokine balance. Shiitake is also one of the few natural dietary sources of ergosterol (provitamin D2), supporting vitamin D status alongside immune function.

Shiitake is classified as Preferred Form by FormulaForge — our top recommendation for Shiitake. It carries a bioavailability rating of good absorption, meaning more of the active compound reaches your tissues per dose unit compared to lower-rated forms.

When choosing a Shiitake supplement, read the label for the specific form name — that is what determines how much you actually absorb. Preferred Forms have the strongest research-backed evidence for efficient absorption.

Other forms may be appropriate depending on individual goals, cost considerations, and your healthcare provider’s guidance. The best form for you depends on your specific health needs.

Individual dose requirements vary based on health goals, body weight, and existing nutrient intake. Your healthcare provider can help you determine an appropriate amount of Shiitake for you.

Side Effects: Consult your healthcare provider regarding tolerability, particularly at higher doses.

These statements are based on structure/function research and have not been evaluated by the Food and Drug Administration. This information is not intended to diagnose, treat, cure, or prevent any disease. Always consult a qualified healthcare provider before starting or changing a supplement regimen.