ByDr. Brennan Commerford, D.C.·Last reviewed: July 2026
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Trimethyl Glycine (TMG) - Betaine Anhydrous: verification pending

We’re confirming the science for this compound before we publish a form ranking. Our team reviews every ranked page against peer-reviewed absorption data — this one is still under review, so we are not showing a score yet.

Check back soon. Rankings are reviewed by Dr. Brennan Commerford, D.C.

References

  1. A randomized, placebo-controlled trial in active young women reported that betaine supplementation was associated with favorable changes in body composition and anaerobic exercise performance, supporting betaine's role in normal muscle and metabolic function during exercise. PubMed
  2. A controlled dietary intervention study reported that increasing betaine intake in healthy adults was associated with higher plasma betaine and lower fasting homocysteine, supporting betaine's role in normal homocysteine metabolism. PubMed
  3. In a human RCT (n=8), supplementary betaine significantly raised plasma betaine versus control (P<0.001) with minimal urinary loss. PubMed
  4. In a human RCT (n=10), oral betaine produced a dose-dependent rise in serum betaine across 1/3/6g doses with negligible urinary excretion. PubMed

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.