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Coffee Fruit Extract: verification pending
We’re confirming the science for this compound before we publish a form ranking. Our team reviews every ranked page against peer-reviewed absorption data — this one is still under review, so we are not showing a score yet.
Check back soon. Rankings are reviewed by Dr. Brennan Commerford, D.C.
References
- In a small industry-funded, randomized controlled comparison (n=10/arm), a single dose of whole coffee fruit concentrate (WCFC, 100 mg) raised plasma BDNF approximately 143% above baseline (more than placebo or matched green-coffee/grape-seed doses) in fasted healthy adults; the effect was acute and the study was not replicated in longer-duration trials at this scale. PubMed
- A randomized, double-blind, placebo-controlled 42-day trial (n=138) of a whole coffee cherry extract plus phosphatidylserine formulation (Neuriva®) found no statistically significant BDNF advantage versus placebo; BDNF — the mechanism this page discusses — was unchanged. (The formulation also contained phosphatidylserine, confounding attribution to coffee fruit alone.) PubMed
- A randomized, double-blind, placebo-controlled 28-day trial (n=52) of a polyphenolic supplement containing whole coffee fruit extract (100 mg) plus Bacopa monnieri and Panax quinquefolius improved positive affect and delayed recall and increased prefrontal-cortex activation versus placebo; because the formulation was multi-herb, the effect cannot be attributed to coffee fruit extract alone. PubMed
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.